Aim: This is a case report of a 4-year-old patient with complete anodontia due to ectodermal dysplasia (ED) using digital planning and printing of a complete denture. Background: ED is a hereditary disorder characterized by the abnormal development of ectodermal tissues, often resulting in anodontia. Traditional treatment methods for anodontia in pediatric patients are challenging and often less effective. Recent advancements in digital technologies offer promising alternatives, providing better outcomes for patients with ED. Case description: A 4-year-old patient diagnosed with complete anodontia due to ED underwent treatment using a three-dimensional (3D) printed complete denture. Advanced digital technologies, including the intraoral scanner and the 3D printer, were utilized in the treatment process. The application of these technologies led to significant improvements in the patient's oral functions, psychological well-being, and overall health. Conclusion: The use of a 3D printed complete denture for a pediatric patient with ED resulted in notable enhancements in oral functionality and quality of life. This case signifies the utility of digital planning and scanning in the fabrication of a denture for pediatric patients with ED. Clinical significance: This case underscores the benefits of 3D printing technology over conventional methods in the treatment of anodontia in pediatric patients with ED. The successful application of these advanced digital technologies demonstrates their potential to revolutionize dental care, providing improved outcomes and enhancing the overall well-being of affected individuals.