International Journal of Clinical Pediatric Dentistry

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VOLUME 18 , ISSUE 1 ( January, 2025 ) > List of Articles

ORIGINAL RESEARCH

Formulation of Tooth Mousse Containing Grape Seed Extract and Comparative Evaluation of Its Physiochemical Properties with the Commercially Available GC Tooth Mousse: An In Vitro Study

Akanksha Gujarathi, Preetam Shah, Shweta Jajoo, Chetana Jagtap, Rucha Dhavalbhakta

Keywords : GC Tooth Mousse, Grape seed extract, Proanthocyanidin, Remineralization

Citation Information : Gujarathi A, Shah P, Jajoo S, Jagtap C, Dhavalbhakta R. Formulation of Tooth Mousse Containing Grape Seed Extract and Comparative Evaluation of Its Physiochemical Properties with the Commercially Available GC Tooth Mousse: An In Vitro Study. Int J Clin Pediatr Dent 2025; 18 (1):100-104.

DOI: 10.5005/jp-journals-10005-3041

License: CC BY-NC 4.0

Published Online: 14-02-2025

Copyright Statement:  Copyright © 2025; The Author(s).


Abstract

Background: The prevalence of total dental caries (untreated and treated) in primary or permanent teeth increases with age, going from 21.4, 50.5, and 53.8% among ages 2–5, 6–11, and 12–19, respectively. Dental caries is a dynamic process of demineralization and remineralization, and the use of various topical and systemic fluoride- and nonfluoride-based remineralizing agents can help replenish lost ions, promoting remineralization and further decreasing the prevalence of caries. Objectives: The aim of this study is to formulate the grape seed extract-containing tooth mousse and to compare its physiochemical properties with the commercially available GC Tooth Mousse. Materials and methods: The methodology involves formulating a tooth mousse incorporating grape seed extract and conducting physicochemical evaluations to compare its properties with those of the commercially available GC Tooth Mousse. Results: Physicochemical parameters of grape seed extract-containing tooth mousse are similar to the gold standard GC Tooth Mousse. Along with that, the slight acidity of the grape seed mousse supports the remineralization process. Conclusion: The study highlights that the grape seed extract-containing mousse offers a promising alternative to the marketed GC Tooth Mousse.


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  1. Furiga A, Lonvaud-Funel A, Badet C. In vitro study of antioxidant capacity and antibacterial activity on oral anaerobes of a grape seed extract. Food Chem 2009;113(4):1037–1040. DOI: 10.1016/j.foodchem.2008.08.059
  2. Ten Cate's Oral Histology: Development, Structure, and Function. 5th ed. St. Louis: Mosby; 1998. p. 150.
  3. Zhou R, Si S, Zhang Q. Water-dispersible hydroxyapatite nanoparticles synthesized in aqueous solution containing grape seed extract. Appl Surf Sci 2012;258(8):3578–3583. DOI: 10.1016/j.apsusc.2011.11.119
  4. Morgan MV, Adams GG, Bailey DL, et al. The anticariogenic effect of sugar-free gum containing CPP-ACP nanocomplexes on approximal caries determined using digital bitewing radiography. Caries Res 2008;42:171–184. DOI: 10.1159/000128561
  5. Lokhande P, Manne D, Shivanna V, et al. Evaluation of 5% proanthocyanidin and 30% alpha-tocopherol on shear bond strength of composite to bleached enamel: an in vitro study. J Dent Res Rev 2018;5:128–131. DOI: 10.4103/jdrr.jdrr_54_18
  6. Preethi N. Remineralizing agent—then and now—an update. Dentistry 2014;4.
  7. Shi JH, Hong L, Wang YN. In vitro remineralization effects of grape seed extract on artificial dentin caries. Shanghai J Stomatol 2015;24(1):18–22.
  8. Sumathy VJH. Antioxidant and antimicrobial activity of grape seed extract. Int J Med Pharm Res 2016;4(5):287–292.
  9. Chavan SS, Ghodake PL. Study of extract herbal toothpaste production. Int J Creat Res Thoughts 2023;11(6):c1–c27.
  10. Ogboji J, Chindo IY, Jauro A, et al. Formulation, physicochemical evaluation and antimicrobial activity of green toothpaste on streptococcus mutans. Int J Adv Chem 2018;6:108. DOI: 10.14419/ijac.v6i1.10808
  11. Adeleye OA, Bamiro O, Akpotu M, et al. Physicochemical evaluation and antibacterial activity of Massularia acuminata herbal toothpaste. Turk J Pharm Sci 2021;18(4):476–482. DOI: 10.4274/tjps.galenos.2020.42966
  12. Toksoy MO, Tugcu-Demiröz F, Tirnaksiz F. Evaluation of rheological and textural properties of toothpastes. FABAD J Pharm Sci 2013;38:135–141.
  13. Jagtap AM, Kaulage SR, Kanse SS, et al. Preparation and evaluation of toothpaste. Asian J Pharm Ana 2018;8(4):191–194. DOI: 10.5958/2231-5675.2018.00035.2
  14. Andrade Junior ACC, Andrade MRTC, Machado WAS, et al. In vitro study of dentrifice abrasivity. Rev Odontol Univ Sao Paulo 1998;12(13):231–236. DOI: 10.1590/S0103-06631998000300006
  15. Joiner A, Pickles MJ, Lynch S, et al. The measurement of enamel wear by four toothpastes. Int Dent J 2008;58(1):23–28. DOI: 10.1111/j.1875-595x.2008.tb00173.x
  16. Vieira A, Ruben JL, Huysmans MC. Effect of titanium tetrafluoride, amine fluoride and fluoride vanish on enamel erosion in vitro. Caries Res 2005;39(5):371–379. DOI: 10.1159/000086843
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