A Comparative Evaluation of the Remineralization Potential of Two Contemporary Bioactive Glass-containing Dentifrices on Artificially Demineralized Human Enamel: An In Vitro Study
Sanjana V Thoutam, Sujay Kumar, Jaya Naidu
Keywords :
Bioactive glass, Elsenz™, Scanning electron microscope with energy dispersive analysis, Shy-NM™, Surface microhardness
Citation Information :
Thoutam SV, Kumar S, Naidu J. A Comparative Evaluation of the Remineralization Potential of Two Contemporary Bioactive Glass-containing Dentifrices on Artificially Demineralized Human Enamel: An In Vitro Study. Int J Clin Pediatr Dent 2024; 17 (4):451-455.
Background: There is limited literature comparing the remineralization potential of these two dentifrices, Elsenz™, which contains fluoro calcium (Ca) phosphosilicate, and Shy-NM™, which contains Ca sodium phosphosilicate, are a few of the remineralizing agents.
Aim: To assess and compare the remineralization potential of Elsenz™ and Shy-NM™ dentifrices on artificially induced carious lesions on permanent teeth, using the Vickers microhardness measuring method and scanning electron microscope (SEM) connected to energy dispersive X-ray analysis after laboratory stimulation of the oral environment employing the pH cycling model.
Materials and methods: A total of 30 sound human premolar teeth were divided into six groups for both parameters. Group I—Elsenz™ dentifrice, group II—Shy-NM™ dentifrice, and group III—control. The surface microhardness (SMH) of the test specimens was evaluated followed by a scanning electron microscope with energy dispersive analysis (SEM-EDAX). The specimens were tested at baseline, demineralization, and remineralization. The collected data were subjected to statistical analysis.
Results: Surface microhardness following remineralization with Elsenz™ was 359 Vickers hardness number (VHN), and with Shy-NM™ was 312 VHN. Elsenz™ showed significantly higher remineralization compared to Shy-NM™ (p = 0.002). The SEM-EDAX of the tooth specimens after remineralization revealed an increase in the Ca weight percentage (wt%) compared with demineralization values, which was statistically significant for both Elsenz™ (45.95 ± 3.55%) and Shy-NM™ (47.24 ± 1.99%), along with an increase in the phosphorus wt%, which was statistically significant for Elsenz™ (20.25 ± 0.95%) compared to Shy-NM™ (19.95 ± 0.59%).
Conclusion: Within the scope of this study, the incorporation of fluoride in bioactive glass (BAG) in Elsenz™ had the potential to remineralize enamel better than Shy-NM™ dentifrice. It can, therefore, be concluded that Elsenz™, when compared with Shy-NM™, would be effective in inhibiting demineralization.
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