Aim: To evaluate and compare acceptability and compliance toward conventional removable appliances and novel vivid pedo appliances in 5–12-year-old children. Materials and methods: A total of 46 children who required treatment with a removable appliance such as a removable orthodontic appliance, habit-breaking appliance, myofunctional appliance, or functional and nonfunctional space maintainers were randomized to either group I—a conventional removable appliance or group II—vivid pedo appliance (colorful/attractive removable appliance). After diagnosis and treatment plan, the appropriate removable appliance was fabricated using plain pink self-cure acrylic in groups I and II, and it was fabricated using clear self-cure acrylic adding colors, designs, and stickers according to the child's preference. Questionnaires were administered to evaluate the acceptability and compliance toward removable appliance therapy on the day of appliance delivery after 1 and 6 months. Result: Acceptance and compliance of vivid pedo appliance was more in children compared to conventional removable appliances. The difference was statistically significant. Conclusion: Vivid pedo appliance improved children's acceptance and compliance toward removable appliance therapy. Clinical significance: Removable appliances are an inevitable part of pediatric dentistry right from the movement of teeth, influencing tooth eruption as well as growth of jaws. The success of removable appliance therapy mostly depends on children's compliance. Therefore, the goal of this study was to ascertain how the esthetic attractiveness of an appliance influences the acceptability of a removable appliance and how it reflects on entire compliance toward removable appliance therapy.