International Journal of Clinical Pediatric Dentistry

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VOLUME 16 , ISSUE 2 ( March-April, 2023 ) > List of Articles

ORIGINAL RESEARCH

Comparative Evaluation of Myristica fragrans Essential Oil-Zinc Oxide Mixture with Zinc Oxide Eugenol in Root Canal Filling of Primary Teeth: An In Vivo Study

Jyothsna V Setty, Ila Srinivasan, Roopashree T Sathiesh

Keywords : Myristica fragrans, Obturation, Primary molar, Pulpectomy, Zinc oxide eugenol

Citation Information : Setty JV, Srinivasan I, Sathiesh RT. Comparative Evaluation of Myristica fragrans Essential Oil-Zinc Oxide Mixture with Zinc Oxide Eugenol in Root Canal Filling of Primary Teeth: An In Vivo Study. Int J Clin Pediatr Dent 2023; 16 (2):237-243.

DOI: 10.5005/jp-journals-10005-2508

License: CC BY-NC 4.0

Published Online: 12-05-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Background: This is a preliminary investigation to assess the efficacy of Myristica fragrans (M. fragrans) as pulpectomy obturation material. Objective: To assess the clinical and radiographic efficacy of M. fragrans as pulpectomy obturating material and compare it with zinc oxide eugenol, the gold standard in the obturation of primary teeth. Materials and methods: This is a triple-blind, randomized, and controlled clinical trial performed on children aged between 4–8 years with primary molars requiring pulpotomy. A total of 50 teeth were randomly assigned into two groups—group I received M. fragrans with zinc oxide eugenol, and group II zinc oxide eugenol. Teeth were then filled with glass ionomer cement and were restored using stainless steel crowns. Clinical and radiographic evaluation was done by a blinded calibrated evaluator at 3, 6, and 12-month follow-up periods. The data obtained were subjected to statistical analysis. Results: Clinical and radiographic success in both groups was 100% throughout the follow-up period. Extruded material in the M. fragrans group showed resorption during the follow-up period. Conclusion: Myristica fragrans (M. fragrans) can be suggested as a pulpectomy obturating material for primary teeth. However, further clinical studies with long-term follow-ups are needed to give more affirmative results.


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  1. Camp JH. Pulp therapy for primary and young permanent teeth. Dent Clin North Am 1984; 28(4):651–668.
  2. Johnson R, Flaitz CM, Hickson MJ, et al. Techniques of pulp therapy for primary and immature permanent teeth. Compend Contin Educ Dent 1980;1:27–35.
  3. Gould JM. Root canal therapy for infected primary molar teeth—preliminary report. ASDC J Dent Child 1972;39(4):269–273.
  4. Mathewson RJ, Primosch RE. Fundamentals of Pediatric Dentistry 3rd ed. Chicago IL: Quintessence Publishing,1955:257–280.
  5. Spedding RH. Root canal treatment for primary teeth. Dent Clin North Am 1973;17(1):105–124.
  6. Andlaw RJ, Rock WP. A Manual of Pediatric Dentistry, 4th ed. Edinburgh: Churchill Livingstone 1996;107–116.
  7. Ito IY, Junior FM, Paula-Silva FW, et al. Microbial culture and checkerboard DNA-DNA hybridization assessment of bacteria in root canals of primary teeth pre- and post-endodontic therapy with a calcium hydroxide/chlorhexidine paste. Int J Paediatr Dent 2011;21(5):353–360. DOI: 10.1111/j.1365-263X.2011.01131.x
  8. Barker BC, Parsons KC, Williams GL, et al. Anatomy of root canals. IV deciduous teeth. Aust Dent J 1975; 20(2):101–106. DOI: 10.1111/j.18347819.1975.tb04337.x.
  9. Mass E, Zilberman UL. Endodontic treatment of infected primary teeth, using Maisto's paste. ASDC J Dent Child 1989;56(2):117–120.
  10. Holan G, Fuks AB. A comparison of pulpectomies using ZOE and KRI paste in primary molars: a retrospective study. Pediatr Dent 1993;15(6):403–407.
  11. Coll JA, Sadrian R. Predicting pulpectomy success and its relationship to exfoliation and succedaneous dentition. Pediatr Dent 1996;18(1):57–63.
  12. Fuks AB, Eidelman E, Pauker N, et al. Root fillings with endoflas in primary teeth: a retrospective study. J Clin Pediatr Dent 2002;27(1):41–45. DOI: 10.17796/jcpd.27.1.pp237453707386m1
  13. Payne RG, Kenny DJ, Johnston DH, et al. Two-year outcome study of zinc oxide-eugenol root canal treatment for vital primary teeth. J Can Den Assoc 1993;59(6):528–530,533–536.
  14. Rifkin AJ. Techniques and materials used in endodontics for primary teeth. J DentAssoc S Afr 1982;37(6):377–381.
  15. Nagja T, Vimal K, Sanjeev A. Myristica fragrans: a comprehensive review. Int J Pharm Sci 2016;8(2):27–30.
  16. Setty JV, Srinivasan I, Sathiesh RT, et al. In vitro evaluation of antimicrobial effect of Myristica fragrans on common endodontic pathogens. J Indian Soc Pedod Prev Dent 2020;38(2):145–151. DOI: 10.4103/JISPPD.JISPPD_214_20
  17. Al-Jumaily EF, Al-Amiry MH. Extraction and purification of terpenes from nutmeg (Myristica fragrans). J Al Nahrain Univer 2012;15(3):151–160. DOI: 10.22401/JNUS.15.3.21
  18. American Academy of Pediatric Dentistry Clinical Affairs Committee-Pulp Therapy subcommittee, American Academy of Pediatric Dentistry Council on Clinical Affairs. Guideline on pulp therapy for primary and young permanent teeth. Pediatr Dent 2016;37(6):244–252.
  19. Rewal N, Thakur AS, Sachdev V, et al. Comparison of endoflas and zinc oxide eugenol as root canal filling materials in primary dentition. J Indian Soc Pedod Prev Dent 2014;32(4):317–321. DOI: 10.4103/0970-4388.140958
  20. RojaRamya KS, Vinay C, Uloopi KS, et al. In vivo evaluation of zinc oxide-propolis mixture as root canal filling material in the primary molars: a 24-month follow-up randomized controlled trial. J Indian Soc Pedod Prev Dent 2020;38(2):171–176. DOI: 10.4103/JISPPD.JISPPD_127_20
  21. Mortazavi M, Mesbahi M. Comparison of zinc oxide and eugenol, and vitapex for root canal treatment of necrotic primary teeth. Int J Paediatr Dent 2004;14(6):417–424. DOI: 10.1111/j.1365-263X.2004.00544.x
  22. Chawla HS, Mani SA, Tewari A, et al. Calcium hydroxide as a root canal filling material in primary teeth—a pilot study. J Indian Soc Pedod Prev Dent 1998;16(3):90–92.
  23. Mani SA, Chawla HS, Tewari A, et al. Evaluation of calcium hydroxide and zinc oxide eugenol as root canal filling materials in primary teeth. ASDC J Dent Child 2000;67(2):142–147.
  24. Damle SG, Nadkarni UM. Calcium hydroxide and zinc oxide eugenol as root canal filling materials in primary molars: a comparative study. Aust Endod J 2005;31(3):114–119. DOI: 10.1111/j.1747-4477.2005.tb00318.x
  25. Garcia-Godoy F. Evaluation of an iodoform paste in root canal therapy for infected primary teeth. ASDC J Dent Child 1987;54(1):30–34.
  26. Castagnola L, Orlay HG. Treatment of gangrene of pulp by Walkhoff's method. Br Dent J 1952;93(9):93–102.
  27. Erausquin J, Muruzabal M. Tissue reaction to root canal fillings with absorbable pastes. Oral Surg Oral Med Oral Pathol 1969;28(4):567–578. DOI: 10.1016/0030-4220(69)90266-7
  28. Finn SB. Morphology of primary teeth. Clinical Pedodontics. 4th ed. Philadelphia: WB Saunders,1995.
  29. Wright GZ. Non-pharmacological management of child behavior. Dentistry for child and adolescent. 8th editionMcDonald RE, Avery DR, Dean JR; Mosby year Book Inc. USA 2004:33.
  30. Saravanan S, Madivanan I, Subashini B, et al. Prevalence pattern of dental caries in the primary dentition among school children. Indian J Dent Res 2005;16(4):140–146. DOI: 10.4103/0970-9290.29907
  31. Sathe PV A textbook of Community Dentistry. 1st ed. Hyderabad; Paras Medical Publisher, 1998:84–94.
  32. Tewari A, Chawla HS. A study of prevalence of dental caries in an urban area of India-Chandigarh. JIDA 1997;49:231–237.
  33. Jawdekar SL, Dandare MP, Nato M, et al. Dental caries susceptibility pattern. JIDA 1989;60:200–203.
  34. Rifkin A. A simple, effective, safe technique for the root canal treatment of abscessed primary teeth. ASDC J Dent Child 1980;47(6):435–441.
  35. Thomas AM, Chandra S, Chandra S, et al. Elimination of infection in pulpectomized deciduous teeth: a short-term study using iodoform paste. J Endod 1994;20(5):233–235. DOI: 10.1016/S0099-2399(06)80284-0
  36. Gupta S, Das G. Clinical and radiographic evaluation of zinc oxide eugenol and metapex in root canal treatment of primary teeth. J Indian Soc Pedod Prev Dent 2011;29(3):222–228.
  37. Ozalp N, Saroglu I, Sonmez H, et al. Evaluation of various root canal filling materials in primary molar pulpectomies: an in vivo study. Am J Dent 2005; 18(6):347–350.
  38. Trairatvorakul C, Chunlasikaiwan S. Success of pulpectomy with zinc oxide-eugenol vs calcium hydroxide/iodoform paste in primary molars: a clinical study. Pediatr Dent 2008;30(4):303–308.
  39. Reddy VV, Fernandes. Clinical and radiological evaluation of zinc oxide-eugenol and Maisto's paste as obturating materials in infected primary teeth— nine months study. J Indian Soc Pedod Prev Dent 1996;14(2):39–44.
  40. Ramar K, Mungara J. Clinical and radiographic evaluation of pulpectomies using three root canal filling materials: an in-vivo study. J Indian Soc Pedod Prev Dent 2010;28(1):25–29. DOI: 10.4103/0970-4388.60481
  41. Subramaniam P, Gilhotra K. Endoflas, zinc oxide eugenol and metapex as root canal filling materials in primary molars—a comparative clinical study. J Clin Pediatr Dent 2011;35(4):365–369. DOI: 10.17796/jcpd.35.4.1377v06621143233
  42. Al-Ostwani AO, Al-Monaqel BM, Al-Tinawi MK, et al. A clinical and radiographic study of four different root canal fillings in primary molars. J Indian Soc Pedod Prev Dent 2016;34(1):55–59. DOI: 10.4103/0970-4388.175515
  43. Jaiswal P, Kumar P, Singh VK, et al. Biological effects of Myristica fragrans. Annu Rev Biomed Sci 2009;11:21–29.
  44. Shafiei Z, Shuhairi NN, Md Fazly Shah Yap N, et al. Antibacterial activity of Myristica fragrans against oral pathogens. Evid Based Complement Alternat Med 2012;2012:825362.
  45. Narasimhan B, Dhake AS. Antibacterial principles from Myristica fragrans seeds. J Med Food 2006;9(3):395–399. DOI: 10.1089/jmf.2006.9.395
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