International Journal of Clinical Pediatric Dentistry

Register      Login

VOLUME 15 , ISSUE S1 ( Special issue-1 (Pediatr Endodont), 2022 ) > List of Articles

RESEARCH ARTICLE

Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial

Charishma Sai Bommareddy, Hemalatha Ramkumar, Senthil Dakshinamurthy, Shankar Paulindraraj, Trophimus Gnanabagyan Jayakaran, Karthika Shankar

Citation Information :

DOI: 10.5005/jp-journals-10005-2128

License: CC BY-NC 4.0

Published Online: 28-02-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim and objective: To evaluate the clinical and radiographic success rates of curcumin, curcumin and calcium hydroxide in equal proportions and calcium hydroxide as an obturation material compared to curcumin and calcium hydroxidet (Metapex). Materials and methods: This study included 64 primary molars with irreversible pulpitis indicated for single visit pulpectomy. After obtaining informed consent from the parents, all the teeth were randomly allocated to one of four groups. Pulpectomy was performed using rubber dam isolation and was obturated. The samples were categorized into the four groups based on obturation material namely, group A: curcumin with calcium hydroxide in equal proportions, group B: curcumin, group C: calcium hydroxide, and group D: Metapex. Clinical and radiographic outcomes were evaluated at time intervals of 10 days, 1 month, 3 months, and 6 months. Data was subjected to statistical analysis. Chi-square tests were used compare the groups. Results: At the end of 6 months, clinical and radiographic success rates of groups A, B, and C showed 81.3%, 61.5%, and 93.8%, respectively, while group D had 100% success rate. Conclusion: Among the four groups, the hierarchy of success rates are as follows: Metapex > calcium hydroxide > curcumin and calcium hydroxide > curcumin. However, various formulations and combinations of curcumin can still be extended with larger sample size. Clinical significance: Curcumin and calcium hydroxide paste can be used as an obturating material with further follow-up studies.


HTML PDF Share
  1. Praveen P, Anantharaj A, Venkataraghavan K, et al. A review of obturating materials for primary teeth. SRM J Res Dent Sci 2011;2(1):42. DOI: 10.15520/ijcrr.v11i08.835
  2. Manzoor R, Manzoor M. Obturating materials in pediatric dentistry: A review. Int J Appl Dent Sci 2021;7(1):175–182. DOI: 10.22271/oral.2021.v7.i1c.1133
  3. Siqueira JF Jr, Lopes HP. Mechanisms of antimicrobial activity of calcium hydroxide: a critical review. Int Endod J 1999;32(5):361–369. DOI: 10.1046/j.1365-2591.1999.00275.x
  4. Dogra S. Comparative evaluation of calcium hydroxide and zinc oxide eugenol as root canal filling materials for primary molars: A clinical and radiographic study. World J Dent 2011; 2(1):231–236. DOI: 10.5005/jp-journals-10015-1088
  5. Balakrishnan R, Dubey S, Dhole TK, et al. Comparative antimicrobial efficacy of Metapex, Metronidazole, BioPure MTAD, Aztreonam on Bacteroides fragilis and Propionibacterium acne. Journal of conservative dentistry: JCD. 2013 Jul;16(4):327. DOI: 10.4103/0972-0707.114361
  6. Najjar RS, Alamoudi NM, El-Housseiny AA, et al. A comparison of calcium hydroxide/iodoform paste and zinc oxide eugenol as root filling materials for pulpectomy in primary teeth: A systematic review and meta-analysis. Clinical and experimental dental research 2019 Jun;30(3):294–310. DOI: 10.1002/cre2.173.eCollection2019Jun
  7. Doneria D, Thakur S, Singhal P, et al. Comparative evaluation of clinical and radiological success of zinc oxide-ozonated oil, modified 3mix-mp antibiotic paste, and vitapex as treatment options in primary molars requiring pulpectomy: An in vivo study. J Indian Soc Pedod Prev Dent 2017;35(4):346. DOI: 10.4103/JISPPD.JISPPD_359_16
  8. Mandrol PS, Bhat K, Prabhakar AR. An in vitro evaluation of cytotoxicity of curcumin against human dental pulp fibroblasts. J Indian Soc Pedod Prev Dent 2016; 34(3):269-272. DOI: 10.4103/0970-4388.186757
  9. Menni AC, Ambati NR, Prasad MG. Clinical and radiographic evaluation of Curcumin Gel mixed Endoflas (CGE) powder as obturating material in primary molars. Brazilian Dental Science 2020 Jan 31; 23(1): 8-p. DOI: 10.14295/bds.2020.v23i1.1733
  10. Subramaniam P, Gilhotra K. Endoflas, zinc oxide eugenol and metapex as root canal filling materials in primary molars—A comparative clinical study. J Clin Pediatr Dent 2011;35(4):365–370. DOI: 10.17796/jcpd.35.4.1377v06621143233
  11. Kencheppa U, Gupta M, Sharma P, et al. Comparison of Antibacterial Efficacy of Combination of Turmeric and Calcium Hydroxide with Three Intracanal Medicaments Comparison of Antibacterial Efficacy of Combination of Turmeric. J Orofac Res 2011; 55 (44):113–117. DOI 10.5005/jp-journals-10026-1193
  12. Nagarathna C, Vishwanathan S, Krishnamurthy NH, et al. Primary molar pulpectomy using two different obturation techniques: A clinical study. Contemp Clin Dent 2018; 9(2):231-236. DOI: 10.4103/ccd.ccd_826_17
  13. Damle SG, Nadkarni UM. Calcium hydroxide and zinc oxide eugenol as root canal filling materials in primary molars: a comparative study. Australian Endodontic Journal 2005 Dec; 31(3):114–119. DOI: 10.1111/j.1747-4477.2005.tb00318.x
  14. Fuks A, Eidelman E, Pauker N. Root fillings with Endoflas in primary teeth: a retrospective study. J Clin Pediatr Dent 2003; 27(1):41–45. DOI: 10.17796/jcpd.27.1.pp237453707386m1
  15. Ramar K, Mungara J. Clinical and radiographic evaluation of pulpectomies using three root canal filling materials: an in-vivo study. J Indian Soc Pedod Prev Dent 2010;28(1):25-29. DOI:10.4103/0970-4388.60481
  16. Mortazavi M, Mesbahi M. Comparison of zinc oxide and eugenol, and Vitapex for root canal treatment of necrotic primary teeth. Int J Paediatr Dent 2004; 14(6):417–424. DOI: 10.1111/j.1365-263X.2004.00544.x
  17. Chawla HS, Mani SA, Tewari A, et al. Calcium hydroxide as a root canal filling material in primary teeth–a pilot study. J Indian Soc Pedod Prev Dent. 1998;16(3):90–92.
  18. Pinto DN, de Sousa DL, AraújoRB, et al. Eighteen-month clinical and radiographic evaluation of two root canal-filling materials in primary teeth with pulp necrosis secondary to trauma. Dent Traumatol 2011; 27(3):221–224. DOI: 10.1111/j.1600-9657.2011.00978.x
  19. Prabhakar AR, Swapnil T, Savita H, et al. Comparison of Antibacterial Efficacy of Calcium Hydroxide Paste, 2% Chlorhexidine Gel and Turmeric Extract as an Intracanal Medicament and their Effect on Microhardness of Root Dentin: An in vitro Study. Int J Clin Pediatr Dent 2013;6(2):171–177. DOI: 10.5005/jp-journals-10005-1213
  20. Hugar SM, Kukreja P, Hugar SS, et al. Comparative evaluation of clinical and radiographic success of formocresol, propolis, turmeric gel, and calcium hydroxide on pulpotomized primary molars: A preliminary study. Int J Clin Pediatr Dent 2017;10(1):18-23. DOI: 10.5005/jp-journals-10005-1400
  21. Purohit RN, Bhatt M, Purohit K, et al. Clinical and radiological evaluation of turmeric powder as a pulpotomy medicament in primary teeth: An in vivo study. Int J Clin Pediatr Dent 2017; 10(1):37-40. DOI: 10.5005/jp-journals-10005-1404
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.