A Comparative Evaluation of Remineralizing Potential of Commonly Used Fluoridated Toothpaste, Herbal Toothpaste, Toothpaste with Zinc Hydroxyapatite, and Toothpaste with Calcium Sucrose Phosphate in Children: A Scanning Electronic Microscopic Study
Aim: The aim of this in vitro study is to evaluate the remineralizing potential of commonly used fluoridated toothpaste, toothpaste with calcium sucrose phosphate, toothpaste with zinc hydroxyapatite, herbal toothpaste, and to compare them.
Background: The process of demineralization and remineralization is balanced and occurs concurrently in the oral cavity, but even a mild disruption in this mechanism could lead to dental caries. Dental caries is a threat in the Third World countries and more common entity in childhood. The caries prevalence is reported to be 41% for children within the age of 2–11 years.
Materials and method: According to previous studies and standard sample size calculating formula the sample size of 48 was calculated, the teeth were subjected to demineralization – remineralization process and were observed under scanning electron microscope.
Results: The outcomes of this study suggest that the remineralizing potential of toothpaste with zinc hydroxyapatite (p = 0.0001*) was highest as compared to toothpaste with fluoride ( p = 0.0087*), herbal toothpaste ( p = 0.9034), and toothpaste with calcium sucrose phosphate (p = 0.0002*).
Conclusion: All the four toothpastes showed an adequate amount of remineralization but the highest amount of remineralization potential was seen with toothpaste containing zinc hydroxyapatite.
Clinical significance: The clinical significance of our study is to give clear and evidence-based idea to the dentist and the parents about the remineralizing toothpaste available in the market for children. Treating demineralization at an initial stage would help to remineralize the tooth structure and thereby limit further destruction of the tooth structure which will preserve the beautiful smile of the child.
Singhal RK, Rai B. Remineralization Potential of Three Tooth Pastes on Enamel Caries J Med Sci 2017: 2017;5(5):664–666. DOI: 10.3889/oamjms.2017.090
Lata S, Varghese N, Varughese JM. Remineralization potential of fluoride and amorphous calcium phosphate-casein phospho peptide on enamel lesions: An in vitro comparative evaluation. J Conserv Dent 2010;13(1):42–46. DOI: 10.4103/0972-0707.62634
Balakrishnan A, Jonathan R, Benin P, et al. Evaluation to determine the caries remineralization potential of three dentifrices: An in vitro study. J Conserv Dent 2013;16(4):375–379. DOI: 10.4103/0972-0707.62634
Poggio C, Gulino C, Mirando M, et al. Preventive effects of different protective agents on dentin erosion: An in vitro investigation. J Clin Exp Dent 2017;9(1):e7–e12. DOI: 10.4317/jced.53129
Kaur G, Sanap AU, Aggarwal SD, et al. Comparative evaluation of two different remineralizing agents on the microhardness of bleached enamel surface: Results of an in vitro study. Indian J Dent Res2015;26(2):176–179. DOI: 10.4103/0970-9290.159154
Bhaskar SN. Orban's Oral Histology and Embryology, 11th edition. St. Louis : Mosby-Year Book, Inc.; 1991. p. 62. ISBN: 9788131238011.
Chi LD. Evidence based dentistry: Clinical review articles. Dent Clin N Am 2017;61(3):533–548. DOI: 10.1016/j.cden.2017.02.003
Malekafzali B, Tadayon N. Comparative evaluation of fluoride uptake rate in the enamel of primary teeth after application of two pediatric dentifrices. J Dent Med Sci 2006;3:135–139. DOI: 10.5005/jp-journals-10005-1361
Clasen AB, Ogaard B, Sønju T. A comparison of the anticaries effect on the primary dentition of two dentifrices containing 250 ppm and 1450 ppm fluoride. Int J Paediatr Dent 1995;5(1):3–8. DOI: 10.1111/j.1365-263x.1995.tb00154.x
Berg HJ, Slayton RL. Early Childhood Oral Health. 1st edition. Philadelphia: Wiley-Blackwell 2009. pp. 14–18. ISBN-13: 9780813824161.
Thaveesangpanich P, Itthagarun A, King NM. The effects of child formula toothpastes on enamel caries using two in vitro pH-cycling models. Int Dent J 2005;55(4):217–223. DOI: 10.1111/j.1875-595x.2005.tb00319.x
Hegazy SA, Salama RI. Antiplaque and remineralizing effects of Biorepair mouthwash: A comparative clinical trial. Pediatr Dent J 2016;26(3):89–94. DOI: 10.1016/j.pdj.2016.05.002
Advani S, Sogi S, Hugar S, et al. Remineralization effects of two pediatric dentifrices and one regular dentifrice on artificial carious lesion in primary teeth: An in vitro study. J Int Soc Prevent Community Dent 2014;4(2):96. DOI: 10.4103/2231-0762.137627
Guggenheim B. Cariology Today – International Congress, 1st edition. Berlin: Karger Publishers; 1983. pp. 113–115. ISBN-13: 9783805537612
White DJ. The application of in vitro models to research on demineralization and remineralization of the teeth. Adv Dent Res 1995;9(3):175–177. DOI: 10.1177/08959374950090030101