International Journal of Clinical Pediatric Dentistry

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VOLUME 14 , ISSUE 2 ( March-April, 2021 ) > List of Articles


Comparative Evaluation of Two Remineralizing Agents on Artificial Carious Lesion Using DIAGNOdent

Dilip Shirly Arjun, Sham S Bhat, Sundeep K Hegde, Vidya S Bhat, Hejamady Tati Ajay Rao, Shenoy S Ramdas

Keywords : Casein phosphopeptide-amorphous calcium phosphate, Customized dentifrice, DIAGNOdent, Remineralization

Citation Information : Arjun DS, Bhat SS, Hegde SK, Bhat VS, Rao HT, Ramdas SS. Comparative Evaluation of Two Remineralizing Agents on Artificial Carious Lesion Using DIAGNOdent. Int J Clin Pediatr Dent 2021; 14 (2):192-195.

DOI: 10.5005/jp-journals-10005-1937

License: CC BY-NC 4.0

Published Online: 30-07-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Purpose: The current in vitro study was conducted to assess the remineralization potential of CPP-ACP and a customized dentifrice (tricalcium-phosphate) on artificial carious lesions using DIAGNOdent. Materials and methods: Fifty-one extracted premolars that satisfied the inclusion criteria were painted using acid-resistant nail varnish. A window of 4 × 4 mm was exposed on the center of the buccal surface of each tooth. After 20 minutes of drying, the baseline reading of enamel specimens was assessed using DIAGNOdent. The teeth were then immersed in a bath of demineralizing solution. An incubation period of 96 hours at 37°C resulted in artificial caries-like lesions on the specimen. Readings of the specimen within the window after demineralization were recorded using DIAGNOdent for all the samples. The specimens were divided into three groups randomly [group I—casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), group II—customized dentifrice, group III—artificial saliva]. Samples were subjected to the daily treatment regimen for a period of 30 days. The samples were evaluated for remineralization by laser fluorescent device (DIAGNOdent) on the 15th and 30th day, respectively. Results: The statistical analysis was done using the Friedman test, Kruskal–Wallis test, Wilcoxon sign rank test, and Mann–Whitney test. The results showed that both CPP-ACP and customized dentifrice showed almost similar remineralization potential but CPP-ACP showed significant remineralization (p < 0.001). Conclusion: The DIAGNOdent observation conclusively proves that CPP-ACP and customized dentifrice remineralizes the demineralized tooth samples in vitro with CPP-ACP showing significant remineralization.

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