International Journal of Clinical Pediatric Dentistry

Register      Login

VOLUME 7 , ISSUE 1 ( January-April, 2014 ) > List of Articles

CASE REPORT

Congenital Epidermal Nevus

Bhawna Arora, Vineet Inder Singh Khinda, Gurlal Singh Brar

Keywords : Epidermal, Nevus, Nevi, Cryosurgery, Dermabrasion

Citation Information : Arora B, Singh Khinda VI, Singh Brar G. Congenital Epidermal Nevus. Int J Clin Pediatr Dent 2014; 7 (1):43-46.

DOI: 10.5005/jp-journals-10005-1232

License: CC BY-NC 4.0

Published Online: 01-10-2018

Copyright Statement:  Copyright © 2014; The Author(s).


Abstract

Epidermal nevi are hamartomas that are characterized by hyperplasia of the epidermis and adnexal structures, and may be associated with serious disfiguration. Germline mutations in the FGFR3 gene have found to be the etiology of epidermal nevus. Patients often seek treatment from dermatologic surgeons but even an alert dentist can help to diagnose the lesion from its clinical appearance. Various treatment modalities are available and it is the clinician's choice to choose depending upon the patient's condition. How to cite this article: Arora B, Khinda VIS, Bajaj N, Brar GS. Congenital Epidermal Nevus. Int J Clin Pediatr Dent 2014;7(1): 43-46.


PDF Share
  1. Brandling-Bennett HA (University of Washington, Seattle Children's Hospital, Seattle, WA 98105, USA), Morel KD. Epidermal nevi. Pediatr Clin North Am 2010 Oct;57(5):1177-
  2. doi: 10.1016/j.pcl.2010.07.004.
  3. Panagiotopoulos A (3rd Dermatology Clinic, Andreas Sygros Hospital for Skin Diseases, Athens, Greece.), Chasapi V, Nikolaou V, Stavropoulos P, Kafouros K, Petridis A, Katsambas A. Assessment of cryotherapy for the treatment of Verrucous Epidermal naevi. Acta Derm Venereol 2009;89(3):292-294. doi: 10.2340/00015555-0610.
  4. Hafner C (Department of Dermatology, University of Regensburg, Germany. christian.hafner@klinik.uni-regensburg. de), Vanoers J, Vogt T, Landthaler M, Stoehr R, Blaszyk H, Hofstaedter F, Zwarthoff E, Hartmann A. Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi. J Clin Invest 2006 Aug;116(8):2201-2207.
  5. Cassetty CT (Ronald O. Perelman Department of Dermatology, New York University, USA), Leonard AL.. Epidermal nevus. Dermatol Online J 2003 Oct;9(4):43.
  6. Levenberg ME, Ermolovich T, Purcell SM. Management of epidermal nevi in the setting of epidermal syndrome. JAOCD 2006;6:58-61.
  7. Kim JJ (Department of Dermatology, Henry Ford Health System, Detroit, MI 48202, USA), Chang MW, Shwayder T. Topical tretinoin and 5-fluorouracil in the treatment of linear verrucous epidermal nevus. J Am Acad Dermatol 2000 Jul;43(1 Pt 1):129-132.
  8. Happle R (Department of Dermatology, Philipp University, Marburg, Germany. happle@med.uni-marburg.de). Gustav Schimmelpenning and the syndrome bearing his name. Dermatology 2004;209(2):84-87.
  9. Adams D(Vita Dermatology and Laser Institute, Red Bluff, CA, USA), Athalye L, Schwimer C, Bender B. A profound case of linear epidermal nevus in a patient with epidermal nevus syndrome. J Dermatol Case Rep 2011 Jun 6;5(2):30-33. doi: 10.3315/jdcr.2011.1069.
  10. Vidaurri-de la Cruz H (Department of Dermatology, National Institute of Pediatrics, Mexico City, Mexico), Tamayo-Sanchez L, Duran-McKinster C, de la Luz Orozco-Covarrubias M, Ruiz-Maldonado R. Epider-mal nevus syndromes: Clinical findings in 35 patients. Pediatr Dermatol 2004 Jul-Aug;21(4):432-439.
  11. García-Vargas A (Instituto Dermatológico de Jalisco “Dr. José Barba Rubio”, Guadalajara, Mexico), Hafner C, Pérez- Rodríguez AG, Rodríguez-Rojas LX, González-Esqueda P, Stoehr R, Hernández-Torres M, Happle R. An epidermal nevus syndrome with cerebral involvement caused by a mosaic FGFR3 mutation. Am J Med Genet A 2008 Sep 1;146A(17):2275-2279. doi: 10.1002/ajmg.a.32429.
  12. Bolognia JL, Orlow SJ, Gilick SA. Lines of Blaschko. J Am Acad Dermatol 1994 Aug;31(2 Pt 1):157-190; quiz 190-192.
  13. Mattei, P. Fundamentals of pediatric surgery. 1st ed. USA: Springer Publication; 2011. 801 p.
  14. Stavrianeas GN, Kakepis EM. Epidermal nevus syndrome. Orphanet Encyclopedia; April 2004.
  15. Eisen DB (Department of Dermatology at the School of Medicine, University of California, Davis, Sacramento, California 95816, USA. dbeisen@ucdavis.edu), Michael DJ. Sebaceous lesions and their associated syndromes: Part II. J Am Acad Dermatol 2009 Oct;61(4):563-578; quiz 579-80. doi: 10.1016/j.jaad.2009.04.059.
  16. Moss C (Department of Paediatric Dermatology, Birmingham Children's Hospital, Birmingham, United Kingdom). Cytogenetic and molecular evidence for cutaneous mosaicism: The ectoderma origin of Blaschko's lines. Am J Med Genet 1999 Aug 6;85(4):330-333.
  17. Lee C, Hsiao C, Chiu H, Tsai T. Acantholytic dyskeratotic epidermal nevus. Indian J Dermatol Venereol Leprol 2011 Mar- Apr;77(2):253. doi: 10.4103/0378-6323.77494.
  18. Rook, A.; Wilkinson, DS.; Ebling, FJB.; Champion, RH.; Burton, JL., editors. Textbook of dermatology. 4th ed. Blackwell Science Ltd: A Blackwell Publishing company; 1986.
  19. Micali G, Nasca MR, Musumeci ML. Effect of topical calcipotriol on inflammatory linear verrucous epidermal nevus. Pediatr Dermatol 1995 Dec;12(4):386-387.
  20. Brown HM, Gorlin RJ. Oral mucosal involvement in nevus unius lateris (Icthyosis Hysterix). Arch Dermatol 1960 Apr;81:509- 515.
  21. Zvulunov A (Soroka Medical Center, Ben-Gurion University, Beer-Sheva Israel), Grunwald MH, Halvy S. Topical calcipotriol for treatment of inflammatory linear verrucous epidermal nevus. Arch Dermatol 1997 May;133(5):567-8.
  22. Boyce S (Washington Institute of Dermatologic Laser Surgery, Washington, DC 20037, USA), Alster T. CO2 laser treatment of epidermal nevi: Long-term success. Dermatol Surg 2002 Jul;28(7):611-4.
  23. Davison SP (Division of Plastic and Reconstructive Surgery, Georgetown University Medical Center, Washington, DC 20007, USA), Khachemoune A, Yu D, Kauffman LC. Nevus sebaceous of Jadassohn revisited with reconstruction options. Int J Dermatol 2005 Feb;44(2):145-150.
  24. Chung A, Lam W. A man with verrucous lesions over the right foot for 30 years: A case of ILVEN. Hong Kong J Dermatol Venereol 2011;19:130-133.
  25. Rulo HF (Department of Dermatology, University Hospital Nijmegen, The Netherlands), van de Kerkhof PC. Treatment of inflammatory linear verrucous epidermal nevus. Dermatologica 1991;182(2):112-114.
  26. Attia A, Elbasiouny M. Treatment of verrucous epidermal nevus using long pulsed Nd:YAG laser. Egyptian Dermatology Online Journal 2010 June;6(1):2.
  27. Alster TS(Georgetown University Medical Center, Washington, DC). Inflammatory linear verrucous epidermal nevus: Successful treatment with the 585 nm flashlamp-pumped pulsed dye laser. J Am Acad Dermatol 1994 Sep;31(3 Pt 1):513-514.
  28. Freedman BM (Plastic Surgery Associates of Northern Virginia, McLean, Virginia 22102, USA), Rueda-Pedraza E, Waddell S. The epidermal and dermal changes associated with microdermabrasion. Dermatol Surg 2001 Dec;27(12):1031-3; discussion 1033-1034.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.