Apert syndrome (acrocephalosyndactyly) is a rare congenital disorder characterized by craniosynostosis, midfacial malformation and symmetrical syndactyly. We present a 10-month-old infant having all the features of classical Apert syndrome.
How to cite this article: Khan S, Chatra L, Shenai P, Veena KM. Apert Syndrome: A Case Report. Int J Clin Pediatr Dent 2012; 5(3):203-206.
Cohen MM Jr (Department of Oral Biology, Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada), Kreiborg S. New indirect method for estimating the birth prevalence of the Apert syndrome. Int J Oral Maxillofac Surg 1992 Apr;21(2):107-109.
Anderson J (School of Biochemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK), Burns HD, Enriquez- Harris P, Wilkie AO, Heath JK. Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand. Hum Mol Genet 1998 Sep;7(9):1475-1483.
Batra P (Dept. of Dental Surgery, All India Institute of Medical Sciences, New Delhi), Duggal R, Prakash H. Dentofacial characteristics in Apert syndrome: A case report. J Indian Soc Pedod Prev Dent 2002 Sep;20(3):118-123.
Cohen MM Jr (Department of Oral Biology, Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada), Kreiborg S. Skeletal abnormalities in the Apert syndrome. Am J Med Genet 1993 Oct 1;47(5):624-632.
Soancã A (Department of Periodontology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania), Dudea D, Gocan H, Roman A, Culic B. Oral manifestations in Apert syndrome: Case presentation and a brief review of the literature. Rom J Morphol Embryol 2010;51(3):581-584.
Carinci F (Department of Maxillofacial Surgery, University of Ferrara, Ferrara, Italy. crc@.unife.it), Pezzetti F, Locci P, Becchetti E, Carls F, Avantaggiato A, Becchetti A, Carinci P, Baroni T, Bodo M. Apert and Crouzon syndromes: clinical findings, genes and extracellular matrix. J Craniofac Surg 2005 May;16(3):361-368.
Ibrahimi OA (Department of Pharmacology and the Institute of Reconstructive Plastic Surgery, New York University School of Medicine, New York, NY 10016, USA), Chiu ES, McCarthy JG, Mohammadi M. Understanding the molecular basis of Apert syndrome. Plast Reconstr Surg 2005 Jan;115(1):264-270.
