International Journal of Clinical Pediatric Dentistry

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VOLUME 9 , ISSUE 1 ( January-March, 2016 ) > List of Articles

Original Article

Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization

Feda I Zawaideh, Arwa I Owais, Wasan Kawaja

Keywords : Aegis®, Amorphous calcium phosphate, Demi-neralization, Pit and fissure sealant, Surface microhardness

Citation Information : Zawaideh FI, Owais AI, Kawaja W. Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization. Int J Clin Pediatr Dent 2016; 9 (1):10-14.

DOI: 10.5005/jp-journals-10005-1325

License: CC BY-NC 4.0

Published Online: 00-03-2016

Copyright Statement:  Copyright © 2016; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: To evaluate the effect of amorphous calcium phosphate (ACP)-containing pit and fissure sealant on inhibition of enamel demineralization in vitro. Materials and methods: Enamel specimens (n = 75) were prepared using freshly extracted noncarious human third molars. Box-shaped cavities (8 × 2 × 2 mm) on the buccal or lingual surfaces were prepared and restored with resin-based sealant (Concise™), ACP-containing sealant (Aegis®) or fluoride-containing sealant (Conseal-F™). The samples were acid challenged in a demineralizing solution of 50 mmol/l lactic acid at pH 5.0 for 4 days. The change in enamel microhardness (ΔSµH) was calculated. Data were analyzed using one-way analysis of variance (ANOVA) and Tukey\'s post hoc test. Results: The mean SµH0 (±SD) (in Vicker\'s unit) prior to the acid challenge was: Concise™ (318.83 ± 33.86), Aegis® (331.03 ± 21.52), Conseal-F™ (310.12 ± 34.31). Following the acid challenge, the values dropped in all groups and ΔSµH (±SD) values were 269.17 ± 47.49, 151.39 ± 23.96 and 175.79 ± 32.39 respectively. Conclusion: The ACP-containing pit and fissure sealant has the potential to inhibit enamel demineralization. How to cite this article: Zawaideh FI, Owais AI, Kawaja W. Ability of pit and fissure sealant-containing amorphous calcium phosphate to inhibit enamel demineralization. Int J Clin Pediatr Dent 2016;9(1):10-14.


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  1. Skrtic D, Hailer AW, Takagi S, Antonucci JM, Eanes ED. Quantitative assessment of the efficacy of amorphous calcium phosphate/methacrylate composites in remineralizing carieslike lesions artificially produced in bovine enamel. J Dent Res 1996 Sep;75(9):1679-1686.
  2. Silva KG, Pedrini D, Delbem AC, Ferreira L, Cannon M. In situ evaluation of the remineralizing capacity of pit and fissure sealants containing amorphous calcium phosphate and/or fluoride. Acta Odontol Scand 2010 Jan;68(1): 11-18.
  3. Langhorst SE, O'Donnell JNR, Skrtic D. In vitro remineralization effectiveness of polymeric ACP composites: quantitative micro-radiographic study. Dent Mater 2009 July;25(7): 884-891.
  4. Schumacher GE, Antonucci JM, O'Donnell JNR, Skrtic D. The use of amorphous calcium phosphate composites as bioactive basing materials. Their effect on the strength of the composite/adhesive/dentin bond. J Am Dent Assoc 2007 Nov;138(11):1476-1484.
  5. Choudhary P, Tandon S, Ganesh M, Mehra A. Evaluation of the remineralization potential of amorphous calcium phosphate and fluoride-containing pit and fissure sealants using scanning electron microscopy. Indian J Dent Res 2012 Mar-Apr;23(2):157-163.
  6. Alsaffar A, Tantbirojn D, Versluis A, Beiraghi S. Protective effect of pit and fissure sealants on demineralization of adjacent enamel. Pediatr Dent 2011 Nov-Dec;33(7):491-495.
  7. Gonzales-Cabezas C, Fontana M, Dunipace AJ, Li Y, Fischer GM, Proskin HM, Stookey GK. Measurement of enamel remineralization using microradiography and confocal microscopy. Caries Res 1998;32(5):385-392.
  8. Kashet S. Historical review of remineralization research. J Clin Dent 1999;10:56-64.
  9. Vatanatham K, Trairatvorakul C, Tantbirojn D. Effect of fluoride- and nonfluoride-containing resin sealants on mineral loss of incipient artificial carious lesion. J Clin Pediatr Dent 2006 Summer;30(4):320-324.
  10. Salar DV, García-Godoy F, Flaitz CM, Hicks MJ. Potential inhibition of demineralization in vitro by fluoride-releasing sealants. J Am Dent Assoc 2007 Apr;138(4):502-506.
  11. Garçía-Godoy F, Summitt JB, Donly KJ. Caries progression of white spot lesions sealed with an unfilled resin. J Clin Pediatr Dent 1997 Winter;21(2):141-143.
  12. Zhou SL, Zhou J, Watanabe S, Watanabe K, Wen LY, Xuan K. In vitro study of the effects of fluoride-releasing dental materials on remineralization in an enamel erosion model. J Dent 2012 Mar;40(3):255-263.
  13. Kantovitz KR, Pascon FM, Correr GM, Borges AF, Uchôa MN, Puppin-Rontani RM. Inhibition of mineral loss at the enamel/sealant interface of fissures sealed with fluoride- and nonfluoride containing dental materials in vitro. Acta Odontol Scand 2006 Nov;64(6):376-383.
  14. Skrtic D, Antonucci JM, Eanes ED, Eichmiller FC, Schumacher GE. Physicochemical evaluation of bioactive polymeric composites based on hybrid amorphous calcium phosphates. J Biomed Mat Res 2000;53(4):381-391.
  15. Xu HH, Weir MD, Sun L. Calcium and phosphate ion releasing composite: effect of pH on release and mechanical properties. Dent Mater 2009 Apr;25(4):535-542.
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