International Journal of Clinical Pediatric Dentistry

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VOLUME 9 , ISSUE 1 ( January-March, 2016 ) > List of Articles

Original Article

Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization

Feda I Zawaideh, Arwa I Owais, Wasan Kawaja

Keywords : Aegis®, Amorphous calcium phosphate, Demi-neralization, Pit and fissure sealant, Surface microhardness

Citation Information : Zawaideh FI, Owais AI, Kawaja W. Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization. Int J Clin Pediatr Dent 2016; 9 (1):10-14.

DOI: 10.5005/jp-journals-10005-1325

License: CC BY-NC 4.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2016; The Author(s).


Aim: To evaluate the effect of amorphous calcium phosphate (ACP)-containing pit and fissure sealant on inhibition of enamel demineralization in vitro. Materials and methods: Enamel specimens (n = 75) were prepared using freshly extracted noncarious human third molars. Box-shaped cavities (8 × 2 × 2 mm) on the buccal or lingual surfaces were prepared and restored with resin-based sealant (Concise™), ACP-containing sealant (Aegis®) or fluoride-containing sealant (Conseal-F™). The samples were acid challenged in a demineralizing solution of 50 mmol/l lactic acid at pH 5.0 for 4 days. The change in enamel microhardness (ΔSµH) was calculated. Data were analyzed using one-way analysis of variance (ANOVA) and Tukey's post hoc test. Results: The mean SµH0 (±SD) (in Vicker's unit) prior to the acid challenge was: Concise™ (318.83 ± 33.86), Aegis® (331.03 ± 21.52), Conseal-F™ (310.12 ± 34.31). Following the acid challenge, the values dropped in all groups and ΔSµH (±SD) values were 269.17 ± 47.49, 151.39 ± 23.96 and 175.79 ± 32.39 respectively. Conclusion: The ACP-containing pit and fissure sealant has the potential to inhibit enamel demineralization. How to cite this article: Zawaideh FI, Owais AI, Kawaja W. Ability of pit and fissure sealant-containing amorphous calcium phosphate to inhibit enamel demineralization. Int J Clin Pediatr Dent 2016;9(1):10-14.

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