Epidermolysis bullosa (EB) is a group of hereditary chronic disorders, characterized by fragility of the skin and mucous membranes in response to minor mechanical trauma. The objective of this study was to report the case of a young girl diagnosed with epidermolysis bullosa simplex (EBS), transmitted by an autosomal dominant gene. Cutaneous findings included blisters and dystrophy following minimal friction. Recurrent blisters and vesicle formation on the hard palate were the main oral findings. In conclusion, publications concerning the oral and clinical manifestations of EBS are important for providing knowledge and an early multidisciplinary approach that prevents blister formation and improves these patients’ quality of life, with the dentist playing an important role in oral health management.
How to cite this article: Scheidt L, Sanabe ME, Diniz MB. Oral Manifestations and Dental Management of Epidermolysis Bullosa Simplex. Int J Clin Pediatr Dent 2015;8(3):239-241.
Williams EF, Gannon K, Soon K. The experiences of young people with epidermolysis bullosa simplex: a qualitative study. J Health Psychol 2011;16(5):701-710.
Komorowski L, Müller R, Vorobyev A, Probst C, Recke A, Jonkman MF, Hashimoto T, Kim SC, Groves R, Ludwig RJ, et al. Sensitive and specific assays for routine serological diagnosis of epidermolysis bullosa acquisita. J Am Acad Dermatol 2013;68(3):e89-95.
Bruckner AL, Bedocs LA, Keiser E, Tang JY, Doernbrack C, Arbuckle HA, Berman S, Kent K, Bachrach LK. Correlates of low bone mass in children with generalized forms of epidermolysis bullosa. J Am Acad Dermatol 2011;65(5):1001-1009.
Intong LR, Murrell DF. Inherited epidermolysis bullosa: new diagnostic criteria and classification. Clin Dermatol 2012; 30(1):70-77.
Pope E, Lara-Corrales I, Mellerio J, Martinez A, Schultz G, Burrell R, Goodman L, Coutts P, Wagner J, Allen U, et al. A consensus approach to wound care in epidermolysis bullosa. J Am Acad Dermatol 2012;67(5):904-917.
Ivanoff CS, Hottel TL. Epidermolysis bullosa acquisita: a rare challenge in dental management. Compend Contin Educ Dent 2012;33(4):238-240.
Santos KKD, Difabio LFG, Santos MTBR, Soares Junior LAV. Effectiveness of oral lubricants in patients with epidermolysis bullosa. RGO 2011;59(2):209-213.
Margari F, Lecce PA, Santamato W, Ventura P, Sportelli N, Annicchiarico G, Bonifazi E. Psychiatric symptoms and quality of life in patients affected by epidermolysis bullosa. J Clin Psychol Med Settings 2010;17(4):333-339.
van Scheppingen C, Lettinga AT, Duipmans JC, Maathuis CG, Jonkman MF. Main problems experienced by children with epidermolysis bullosa: a qualitative study with semistructured interviews. Acta Derm Venereol 2008;88(2):143-150.
Fortuna G, Chainani-Wu N, Lozada-Nur F, Aria M, Cepeda- Valdes R, Pollio A, Marinkovich MP, Martinez-Salazar AE, Mignogna MD, Bruckner AL, et al. Epidermolysis Bullosa Oropharyngeal Severity (EBOS) score: a multicenter development and reliability assessment. J Am Acad Dermatol 2013;68(1):83-92.
Babaee N, Zabihi E, Mohseni S, Moghadamnia AA. Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis. Dent Res J 2012;9(4):381-385.
Habeeb F, Shakir E, Bradbury F, Cameron P, Taravati MR, Drummond AJ, Gray AI, Ferro VA. Screening methods used to determine the anti-microbial properties of Aloe vera inner gel. Methods 2007;42(4):315-320.
Kummer TR, Nagano HC, Tavares SS, Santos BZ, Miranda C. Oral manifestations and challenges in dental treatment of epidermolysis bullosa dystrophica. J Dent Child 2013;80(2): 97-100.