Aim: The present study was undertaken to compare two methods of obturation in primary teeth by using lentulospirals and pressure syringe, radiographically. Materials and methods: Sixty teeth in subjects with mean age of 5.88 ± 1.58 years were obturated randomly using two different obturating techniques, i.e. group I: Thirty teeth obturated with pressure syringe, and group II: Thirty teeth obturated with lentulospiral. Quality of obturation and presence or absence of voids were assessed by taking radiographs after obturation was done using both the techniques. Results of quality of obturation were statistically analyzed using Chi-square test and Mann-Whitney's test, whereas voids were analyzed using Chi-square test. Results: No statistically significant difference between the quality of obturation using pressure syringe or lentulospiral (p > 0.05) was observed. However, significantly higher number of voids were found for lentulospiral technique as compared to pressure syringe (p < 0.01). Conclusion: Both the techniques were found to be equally efficient statistically, though lentulospiral produced more voids. How to cite this article: Vashista K, Sandhu M, Sachdev V. Comparative Evaluation of Obturating Techniques in Primary Teeth: An in vivo Study. Int J Clin Pediatr Dent 2015;8(3):176-180.