Idiopathic gingival fibromatosis is a rare heriditary condition characterized by slowly progressive, nonhemorrhagic, fibrous enlargement of
maxillary and mandibular keratinized gingiva caused by increase in submucosal connective tissue elements. This case report gives an
overview of gingival fibromatosis in a 11-year-old female patient who presented with generalized gingival enlargement. Based on the history
and clinical examination, the diagnosis was made and the enlarged tissue was surgically removed. The patient was being regularly monitored
clinically for improvement in her periodontal condition as well as for any recurrence of gingival overgrowth.
Hereditary gingival fibromatosis: Report of an extensive four generation pedigree. Oral Surg Oral Med Oral Pathol 1998;86:304-07
Familial gingival fibromatosis with unusual histological findings. J Periodontol 1995;66(11):1008-11
Early onset of hereditary gingival fibromatosis in a 28-month old. Pediatr Dent 2009;31(4):286-88
Idiopathic gingival fibromatosis–a neglected case. Indian J Raiologiol Imaging 2002;12:335-38
Br Med J 1969;3:218-19
A mutation in the SOS-1 gene causes hereditary gingival fibromatosis. Type 1. Am J Hum Genet 2002;70;943-954
Evidence of genetic heterogeneity for hereditary gingival fibromatosis. J Dent Res 2000; 79(10):1758-64
A new locus for hereditary gingival fibromatosis (GINGF2) maps to 5q13-q22. Genomics 2001;74(2):180-85
Genetic heterogeneity of gingival fibromatosis on chromosome 2p. J Med Genet 1999;36:683-86
Keratinocytes modify fibroblast metabolism in HGF. Arch Oral Biol 2008;53(11):1050-57
Increased proliferation, collagen and fibronectin production by hereditary gingival fibromatosis fibroblasts. J Periodontol 1997;68(6):524-30
Hereditary gingival fibromatosis: Review of the literature and a case report. Quintessence Int 2000;31:415-18
Gingival abnormalities of genetic origin. A preliminary communication with special reference to hereditary generalized gingival fibromatosis. J Dent Res 1966;45:597-612
Idiopathic gingival fibromatosis: A case report. Hong Kong Dent J 2006;3:53-57
Hereditary gingival hyperplasia. Oral Surg Oral Med Oral Pathol 1965;19:1-4