Background: Pulp capping is a vital dental procedure used to preserve the vitality of teeth affected by deep caries lesions without irreversible pulpitis. The use of modern bioceramic materials has enhanced the predictability of vital pulp therapy (VPT). Aim: This study aimed to assess the clinical success of Biodentine, modified NeoPutty mineral trioxide aggregate (MTA), and calcium hydroxide (Ca(OH)2) as pulp capping materials for indirect pulp capping in carious primary teeth. Materials and methods: Indirect pulp treatment (IPT) was performed on 36 deciduous molars in 36 patients presenting with deep carious lesions. The teeth were randomly assigned to three groups: Biodentine (12 teeth), NeoPutty MTA (12 teeth), and Ca(OH)2 (12 teeth). Patients were monitored at 1, 3, and 6 months post-treatment to evaluate the clinical success of the procedures. Statistical analysis: Statistical analysis was conducted using Statistical Package for the Social Sciences (SPSS) software version 21.0. Pearson's Chi-squared test was employed to compare success and failure rates among Biodentine, MTA, and Ca(OH)2 at three different time intervals (30, 90, and 180 days) and overall success and failure rates regardless of the time intervals. Results: In the statistical analysis, different pulp capping materials yielded varying success rates. The NeoPutty MTA group demonstrated a success rate of 91.67%, the Biodentine group 83.33%, and the Ca(OH)2 group 58.33% after 6 months. However, these differences were not statistically significant. Conclusion: Indirect pulp treatment with calcium silicate-based materials, such as Biodentine and modified NeoPutty MTA, showed superior results compared to the use of calcium hydroxide (Ca(OH)2). Although differences in success rates were observed among the materials, they did not reach statistical significance.