International Journal of Clinical Pediatric Dentistry

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VOLUME 17 , ISSUE 2 ( February, 2024 ) > List of Articles


Thurston Syndrome: An Insight of a Rare Case and Literature Review

Dhwani Sreekumar, Brahmananda Dutta, Kanika S Dhull, Lipsa Bhuyan

Keywords : Case report, Oral-facial-digital syndrome, Polydactyly, Thurston syndrome

Citation Information : Sreekumar D, Dutta B, Dhull KS, Bhuyan L. Thurston Syndrome: An Insight of a Rare Case and Literature Review. Int J Clin Pediatr Dent 2024; 17 (2):206-210.

DOI: 10.5005/jp-journals-10005-2764

License: CC BY-NC 4.0

Published Online: 22-04-2024

Copyright Statement:  Copyright © 2024; The Author(s).


This article reports an infant presented with multiple congenital abnormalities, which is considered a rare case. A 2-month-old girl presented with cleft palate, lobulated tongue, frontal bossing, postaxial polydactyly of hands, and other clinical manifestations involving oral, facial, and digital malformations. Hence, a provisional diagnosis of oral-facial-digital syndrome (OFDS), a rare genetic disorder, was contemplated. A genetic test was undertaken, and a confirmatory diagnosis of OFDS type-V (Thurston syndrome) was made. A brief description of the case and literature review of OFDS, including various aspects like etiology, inheritance, clinical features, and management, are discussed here.

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