Aim and background: Angioedema is a nonpruritic swelling that typically affects the skin, mucous membranes of the face, and perioral soft tissues. It can be life-threatening, but it is usually not and can be treated conservatively unless the airway is compromised. This paper seeks to illuminate a rare case of hereditary angioedema (HAE) onset following dental procedures in a 9-year-old Indian boy. Case description: A 9-year-old male patient reported a chief complaint of spacing in the upper anterior region, which was diagnosed to be due to impacted supernumeraries. Two days after the oral surgical procedure, the child developed symptoms of periorbital edema with facial swelling. A second episode occurred a day after the delivery of the orthodontic appliance. This was also associated with facial swelling, respiratory distress, and gastrointestinal (GI) symptoms. A diagnosis of angioedema was confirmed and was treated appropriately. Conclusion: Dental professionals must be aware of the possibility of triggering AE, a potentially fatal condition in patients. This case highlights the importance of comprehensive medical history intake and timely physician collaboration when confronting unexpected symptoms following a dental procedure. Clinical significance: Awareness of rare conditions like HAE can aid dental professionals in early identification and appropriate management, preventing dangerous exacerbations and contributing to safer dental care.