International Journal of Clinical Pediatric Dentistry

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VOLUME 15 , ISSUE S2 ( Special Issue-2 (Cariology), 2022 ) > List of Articles


Prebiotics—A Primeval Measure to Combat Dental Caries: A Short-term Clinical Study

Sapna Konde, Shruthi Ravindran, Manisha Agarwal, Preetha Peethambar

Keywords : Immunoglobulin A, Prebiotics, Probiotics, Streptococcus mutans, Synbiotics

Citation Information :

DOI: 10.5005/jp-journals-10005-2165

License: CC BY-NC 4.0

Published Online: 16-03-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Background: Prevention of dental caries is paramount in reducing the global burden of the disease. The consumption of probiotics as a prophylactic and therapeutic agent for dental caries, has certain limitations. Prebiotics are nondigestible food ingredients, that enhance the growth and activity of probiotic microorganism, thereby help in the establishment of a healthy oral environment. Aim: The aim of this study was to evaluate and compare the effect of prebiotics, probiotics, and synbiotics on the salivary Streptococcus mutans (S. mutans) counts and salivary IgA concentrations. Methodology: Children of age-group 6–9 years with DMFT score of 5 and above were divided into three groups of 10 each: Group 1 (prebiotics), Group 2 (probiotics), and Group 3 (synbiotics). The functional food therapy was done for a period of 1 month twice daily. The S. mutans count and IgA concentrations were assessed pre- and postintervention. The obtained results were subjected to statistical analysis. Results: A statistically significant reduction of S. mutans was seen in all three groups after 1 month. However, no statistically significant difference was noted between the groups. Conclusion: Prebitoics can serve as an unfortified and natural means of combating dental caries.

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