Oral Angioleiomyoma in Early Childhood Patient: A Case Report of an Uncommon Lesion and Literature Review
Thâmara MM Bezerra, Filipe N Chaves, Francisco SR Carvalho, Fábio WG Costa, Ana PNN Alves, Mário RL Mota, Karuza MA Pereira
Citation Information :
Bezerra TM, Chaves FN, Carvalho FS, Costa FW, Alves AP, Mota MR, Pereira KM. Oral Angioleiomyoma in Early Childhood Patient: A Case Report of an Uncommon Lesion and Literature Review. Int J Clin Pediatr Dent 2021; 14 (6):828-832.
Leiomyoma is a benign soft tissue tumor originating from smooth muscle, rarely seen in the oral cavity, due to the scarcity of this tissue in the mouth. The tumor may occur at any age, without sex predilection. Rare reports of this lesion have been in pediatric patients. The lesion is typically asymptomatic and has slow growth, the final diagnosis is defined by histopathological and immunohistochemical examination. Treatment involves resection of the lesion. The lesion is classified histologically as solid leiomyomas, angioleiomyomas (AL), or epithelioid leiomyomas. We report the case of a 1-year-old female child with a painless papule on the hard palate. Histopathological examination revealed biphasic LA showing proliferation of spindle-shaped nuclear cells in straw-shaped bundles or a concentric design. This is the fourth documented case of AL in early childhood.
Eley KA, Alroyayamina S, Golding SJ, et al. Angioleiomyoma of the hard palate: report of a case and review of the literature and magnetic resonance imaging findings of this rare entity. Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Aug;114(2):e45–e49. DOI: 10.1016/j.oooo.2012.01.014
Reddy BVR, Shoba Rani B, Anuradha CH, et al. Leiomyoma of the mandible in a child. J Oral Maxillofac Pathol 2011;15:101–104. DOI: 10.4103/0973-029X.80015
Radhakrishna M, Varghese S, Sreenivasan B, et al. Angiomyoma of the hard palate – report of a rare case. Int Arab J Dent 2015;6:37–39. Retrieved from https://journals.usj.edu.lb/iajd/article/view/200
World Health Organization. Pathology and genetics of tumors of soft tissue and bone. Lyon: IARC 2002.
Kim YH, Jang YW, Pai H, et al. Congenital angiomyoma of the tongue: case report. Dentomaxillofac Radiol 2010 Oct;39(7):446–448. DOI: 10.1259/dmfr/32524441
Tatehara S, Sato T, Mishima K, et al. Angioleiomyoma of the hard palate: Report of a case and review of literature. J Oral Maxillofac Surg Med Pathol 2013;25(3):282–286. DOI: 10.1016/j.ajoms.2012.05.002
Pandya M, Rao DS, Mamatha GP, et al. Angiomyoma – a requisite in differential diagnosis of palatal growths. Int J Health Sci (Qassim) 2019;13(6):47–49 PMID: 31745398.
Hung KF, Yan AH, Kao SY, et al. Angioleiomyoma in right lingual gingiva- a case report. Chin J Oral Maxillofac Surg 2005;16:179–187. DOI: 10.7104/CJOMS.200509.0179
Wertheimer-Hatch L, Hatch III GF, Hatch KF, et al. Tumors of the oral cavity and pharynx. World J Surg 2000;24(4):395–400. DOI: 10.1007/s002689910064
Toida M, Koizumi H, Shimokawa K. Painful angiomyoma of the oral cavity: report of a case and review of the literature. J Oral Maxillofac Surg 2000;58(4):450–453. DOI: 10.1016/s0278-2391(00)90935-2
Brooks JK, Nikitakis NG, Goodman NJ, et al. Clinicopathologic characterization of oral angioleimyomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94(2):221–227. DOI: 10.1067/moe.2002.125276
Ramesh P, Annapureddy SR, Khan F, et al. Angioleiomyoma: a clinical, pathological and radiological review. Int J Clin Pract 2004;58(6):587–591. DOI: 10.1111/j.1368-5031.2004.00085.x
Giudice A, Bennardo F, Buffone C, et al. Clinical and immunohistochemical features of oral angioleiomyoma: a comprehensive review of the literature and report of a case in a young patient. Case Rep Dent 2019;2498353. DOI: 10.1155/2019/2498353
Chang L, Rao N, Bernthal N, et al. An unusual karyotype in leiomyoma: case report and literature review. J Orthop 2015;12(Suppl 2):S251–S254. DOI: 10.1016/j.jor.2015.10.016
Manor E, Sion-Vardy N, Nash M, et al. Angiomyoma of buccal vestibule: a rare case with a normal karyotype. J Laryngol Otol 2007;121(12):1210–1212. DOI: 10.1017/S0022215107008808
