Citation Information :
Nagaveni N, Poornima P, Soni AJ, Khan MM. A Comparative Evaluation of Revascularization Done in Traumatized Immature, Necrotic Anterior Teeth with and without Platelet-rich Fibrin: A Case Report. Int J Clin Pediatr Dent 2020; 13 (1):98-102.
The aim of this paper is to present two methods of revascularization done in traumatized immature, nonvital anterior teeth using platelet-rich fibrin (PRF) and natural blood clot as a scaffold material. This was performed after disinfection of the root canal space using tri-antibacterial paste. In one tooth, PRF prepared from autologous blood was placed in the canal and in the other tooth, natural bleeding was induced to obtain a fresh blood clot. The patient was recalled regularly at 1, 3, 6, 9, and 12 months’ interval for evaluation. After 12 months, on clinical examination, both teeth showed negative response to percussion and palpation tests but positive response to cold and electric pulp tests. On radiographic examination, the tooth treated with PRF exhibited comparatively faster root lengthening, complete closure of the root apex, more thickening of the root dentinal walls, and narrowing of root canal space compared to conventionally revascularized tooth.
Resenberg B, Murry PE, Namerow K. The effect of calcium hydroxide root filling on dentine fracture strength. Dent Traumatol 2007;23:26–29.
Shabahang S, Torabinezad M. Treatment of teeth with open apices using mineral trioxide aggregate. Pract Periodontics Aesthet Dent 2000;12(3):315–320.
Cotti E, Mereu M, Lusso D. Regenerative treatment of an immature, traumatized tooth with apical periodontitis: report of a case. J Endod 2008;34(5):611–616. DOI: 10.1016/j.joen.2008.02.029.
Wigler R, Kaufman AY, Lin S, et al. Revascularization: a treatment for permanent teeth with necrotic pulp and incomplete root development. J Endod 2013;39(3):319–326. DOI: 10.1016/j.joen.2012.11.014.
Nevins A, Crespi P. A clinical study using the collagen gel Zyplat in endodontic treatment. J Endod 1998;24(9):610–613. DOI: 10.1016/S0099-2399(98)80121-0.
Jadhav G, Shah N, Logani A. Revascularization with and without platelet-rich plasma in nonvital, immature, anterior teeth: a pilot clinical study. J Endod 2012;38(12):1581–1587. DOI: 10.1016/j.joen.2012.09.010.
Hargreaves K, Geisler T, Henry M. Regeneration potential of the permanent tooth: what does the future hold? J Endod 2008;34(7 Suppl):51–56. DOI: 10.1016/j.joen.2008.02.032.
Choukroun J, Adda F, Schoeffler C, et al. An opportunity in paroimplantologie: the PRF. Implantodontie 2001;42:55–63-2.
Nagaveni NB, Parameswarappa P, Joshi JS, et al. Revascularization of immature, nonvital permanent tooth using platelet-rich fibrin in children. Pediatr Dent 2015;37(1):1–6.
Johns DA, Shivashankar VY, Krishnamma S, et al. Use of photo activated disinfection and platelet-rich fibrin in regenerative endodontics. J Conserv Dent 2014;17(5):487–490. DOI: 10.4103/0972-0707.139850.
Keswani D, Pandey RK. Revascularization of an immature tooth with a necrotic pulp using platelet-rich fibrin: a case report. Inter Endod J 2013;46(11):1096–1104. DOI: 10.1111/iej.12107.
Mishra N, Narang I, Mittal N. Platelet-rich fibrin mediated revitalization of immature necrotic tooth. Contemp Clin Dent 2013;4(3):412–415. DOI: 10.4103/0976-237X.118379.
Shivashankar VY, Johns DA, Vidyanath S, et al. Platelet rich fibrin in the revascularization of tooth with necrotic pulp and open apex. J Conserv Dent 2012;15(4):395–398. DOI: 10.4103/0972-0707.101926.
Nagaveni NB, Pathak S, Poornima P, et al. Revascularization induced maturogenesis of nonvital immature permanent tooth using platelet rich fibrin. A case report. J Clin Pediatr Dent 2016;40(1):26–30. DOI: 10.17796/1053-4628-40.1.26.
Trope M. Treatment of the immature teeth with non-vital pulps and apical periodontitis. Dent Clin North Am 2010;54(2):313–324. DOI: 10.1016/j.cden.2009.12.006.
Petrino JA, Boda KK, Shambarger S, et al. Challenges in regenerative endodontics: a case series. J Endod 2010;36(3):536–541. DOI: 10.1016/j.joen.2009.10.006.
Ding RY, Cheung GS, Chen J, et al. Pulp revascularization of immature teeth with apical periodontitis: a clinical study. J Endod 2009;35(5):745–749. DOI: 10.1016/j.joen.2009.02.009.
Dohan DM, Choukroun J, Diss A, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. part I: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101(3):e37–e44. DOI: 10.1016/j.tripleo.2005.07.008.
Dohan DM, Choukroun J, Diss A, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101(3):e45–e50. DOI: 10.1016/j.tripleo.2005.07.009.
Huang FM, Yang SF, Zhao JH, et al. Platelet-rich fibrin increases proliferation and differentiation of human dental pulp cells. J Endod 2010;36(10):1628–1632. DOI: 10.1016/j.joen.2010.07.004.
Lucarelli E, Beretta R, Dozza B, et al. A recently developed bifacial platelet rich fibrin matrix. Eur Cell Mater 2010;20:13–23. DOI: 10.22203/ecm.v020a02.
Tsay R, Vo J, Burke A, et al. Differential growth factor retention by platelet-rich plasma composites. J Oral Max Surg 2005;63(4):521–528. DOI: 10.1016/j.joms.2004.09.012.
American Association of Endodontics. Considerations for regenerative procedures. Available at: http://www.aae.org/Professionals/Content.aspx?id=3496&terms=revascularization. Accessed January 2, 2013.
Geeta IB, Galagali G, Kulkarni S, et al. A natural meliorate: Revolutionary tissue engineering in endodontics. J Clin Diagn Res 2013;7(11):2644–2646. DOI: 10.7860/JCDR/2013/6915.3638.