International Journal of Clinical Pediatric Dentistry

Register      Login

VOLUME 13 , ISSUE 1 ( January-February, 2020 ) > List of Articles

Original Article

A Comparative Evaluation of Two Commonly Used GP Solvents on Different Epoxy Resin-based Sealers: An In Vitro Study

Sakshi Tyagi, Ekta Choudhary, Rajat Chauhan

Keywords : Endodontic solvents, Microhardness, Resin-based sealers

Citation Information : Tyagi S, Choudhary E, Chauhan R. A Comparative Evaluation of Two Commonly Used GP Solvents on Different Epoxy Resin-based Sealers: An In Vitro Study. Int J Clin Pediatr Dent 2020; 13 (1):35-37.

DOI: 10.5005/jp-journals-10005-1741

License: CC BY-NC 4.0

Published Online: 25-12-2015

Copyright Statement:  Copyright © 2020; The Author(s).


Aim: This study evaluates epoxy resin-based sealers after their final set, immersed in Endosolve-R or xylene for 1–2 minutes, for its easy removal mechanically after softening. Materials and methods: Sixty Teflon molds were grouped with 20 samples in each of the three commercially available sealers, i.e., AH 26, AH Plus, and Adseal. The sealers were put in the specific molds after their manipulation as per the instructions given in the literature by the manufacturer. They were allowed to harden for 2 weeks at 37°C in 100% humidity. Two subgroups, A-Xylene and B-Endosolv-R, of 10 samples each, were formed from 20 set specimens based on solvents to which they were immersed for 1 and 2 minutes, respectively. The data obtained was subjected to the Mauchly's test one-way ANOVA and two-way ANOVA for analysis. Results: It was proved that for all the sealers immersed in solvents, there was a significant reduction in the mean Vickers hardness as the time increases. There was a significant difference in the initial hardness between the mentioned sealers with AH plus showing the highest followed by AH 26 and Adseal showing the lowest. AH Plus and Adseal sealers were softened by xylene after 2 minutes of their initial microhardness (p < 0.001); least effect was seen on AH 26. After 2 minutes, Endosolv-R softened initial microhardness of all the three sealers (p < 0.001). Conclusion: It was concluded that Endosolv-R was more effective in softening the epoxy-based resin sealer than xylene, after 2 minutes of exposure.

PDF Share
  1. Rubino GA, Akisue E, Nunes BG, et al. Solvency capacity of gutta-percha and resilon using chloroform, eucalyptol, orange oil or xylene. J Health Sci Inst 2012;30:22–25.
  2. Hülsmann M, Bluhm V. Efficacy, cleaning ability and safety of different rotary NiTi instruments in root canal retreatment. Int Endod J 2004;37(7):468–476. DOI: 10.1111/j.1365-2591.2004.00823.x.
  3. Kfir A, Tsesis I, Yakirevich E, et al. The efficacy of five techniques for removing root filling material: microscopic versus radiographic evaluation. Int Endod J 2012;45(1):35–41. DOI: 10.1111/j.1365-2591.2011.01944.x.
  4. Punitha PG, Shashikala K. Evaluation of adaptation of resin based sealers Epiphany, AH plus and AH 26 to the root canal dentin by scanning electron microscope. Indian J Stomatol 2011;2:207–211.
  5. Duncan HF, Chong BS. Removal of root filling materials. Endod Topic 2008;19(1):33–57. DOI: 10.1016/j.bbapap.2007.08.017.
  6. Ramzi H, Shokouhinejad N, Saghiri MA, et al. Efficacy of three different methods in the retreatment of root canals filled with Resilon/Epiphany SE. Iran Endod J 2010;5(4):161–166.
  7. Grossman. Grossman's Endodontic Practice. 12th ed., New Delhi: Wolters Kluwer; 2010. pp. 278–307.
  8. Shin SJ, Lee Y, Park JW. Evaluation of retrievability using a new soft resin based root canal filling material. J Korean AcadConserv Dent 2006;31(4):323–329. DOI: 10.5395/JKACD.2006.31.4.323.
  9. Taşdemir T, Yildirim T, Celik D. Comparative study of removal of current endodontic fillings. J Endod 2008;34(3):326–329. DOI: 10.1016/j.joen.2007.12.022.
  10. Ruddle CJ, (2001). Nonsurgical retreatment of endodontic failures: treatment concepts and considerations. Endodontic therapy. Available from [Accessed June 2017].
  11. Bodrumlu E, Uzun O, Topuz O, et al. Efficacy of three techniques in removing root canal filling material. J Can Dent Assoc 2008;74(8):721.
  12. Lee KW, Williams MC, Camps JJ, et al. Adhesion of endodontic sealer to dentin and gutta-percha. J Endod 2002;28(10):684–688. DOI: 10.1097/00004770-200210000-00002.
  13. Mamootil K, Messer HH. Penetration of dentinal tubules by endodontic sealer cements in extracted teeth and in vivo. Int Endod J 2007;40(11):873–881. DOI: 10.1111/j.1365-2591.2007.01307.x.
  14. Kim CK, Ryu HW, Chang HS, et al. Evaluation of the radiopacity and cytotoxicity of resinous root canal sealers. J Korean Acad Conserv Dent 2007;32(5):419–425. DOI: 10.5395/JKACD.2007.32.5.419.
  15. Kfir A, Rosenberg E, Tamse A, et al. Can epoxy resin-based endodontic sealers be softened within 1-2 min? An in vitro study with chloroform and xylene. Endod Pract Today 2012;6:189–194.
  16. Vranas RN, Hartwell GR, Moon PC. The effect of endodontic solutions on resorcinol-formalin paste. J Endod 2003;29(1):69–72. DOI: 10.1097/00004770-200301000-00019.
  17. Shokouhinejad N, Sabeti MA, Hasheminasab M, et al. Push-out bond strength of resilon/epiphany self-etch to intraradicular dentin after retreatment: a preliminary study. J Endod 2010;36(3):493–496. DOI: 10.1016/j.joen.2009.11.009.
  18. Jacob S, Lakshmi Narayann L. Effect of chloroform, xylene and halothane on enamel and dentin micro-hardness of human teeth. Endodontol 2000;12:3–6.
  19. Hansen MG. Relative efficiency of solvents used in endodontics. J Endod 1998;24(1):38–40. DOI: 10.1016/S0099-2399(98)80211-2.
  20. Mushtaq M, Masoodi A, Farooq R, et al. The dissolving ability of different organic solvents on three different root canal sealers: in vitro study. Iran Endod J 2012;7(4):198–202.
  21. Gambrel MG, Hartwell GR, Moon PC, et al. The effect of endodontic solution on resorcinol-formalin paste in teeth. J Endod 2005;31(1):25–29. DOI: 10.1097/01.don.0000147783.02453.82.
  22. U.S. Department of Labor (1978). Occupational safety and health guideline for Xylene. [online].CDC website. Available from [Accessed June 2017].
  23. Chutich MJ, Kaminski EJ, Miller DA, et al. Risk assessment of the toxicity of solvents of gutta-percha used in endodontic retreatment. J Endod 1998;24(4):213–216. DOI: 10.1016/S0099-2399(98)80098-8.
  24. Spécialités Septodont: Endosolv. Product for removing canal fillings.[online]Available from:
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.