International Journal of Clinical Pediatric Dentistry

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VOLUME 12 , ISSUE 5 ( September-October, 2019 ) > List of Articles

RESEARCH ARTICLE

Impact of Secretory Immunoglobulin A Level on Dental Caries Experience in Asthmatic Children

Abla Arafa, Salwa AlDahlawi, Adel Hussien

Keywords : Children, Dental caries, Saliva, Secretory immunoglobulin A,Asthma

Citation Information : Arafa A, AlDahlawi S, Hussien A. Impact of Secretory Immunoglobulin A Level on Dental Caries Experience in Asthmatic Children. Int J Clin Pediatr Dent 2019; 12 (5):414-418.

DOI: 10.5005/jp-journals-10005-1663

License: CC BY-NC 4.0

Published Online: 00-10-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Objectives: To assess the association between different factors in saliva and dental caries experience in children with bronchial asthma. Materials and methods: A total of 60 asthmatic children and 60 healthy controls of both genders with age ranging from 4- to 12-year-old. The asthmatics were grouped according to disease severity into mild, moderate, or severe asthma. All the children were clinically examined to assess their dental caries experience (deft/DMFT), and stimulated saliva samples were collected to measure the saliva pH, flow rate, ά-amylase, and secretory immunoglobulin A (sIgA)-level changes. The data were statistically analyzed using the SPSS program (v. 23) to test for significance at p ≤ 0.05. Results: Asthmatic children presented significantly higher deft mean value (6.77 ± 1.69), as well as significantly reduced stimulated saliva flow (0.82 ± 0.2) and sIgA (29.42 ± 6.31) when compared to healthy control. The sIgA of asthmatics showed statistically significant negative correlation with deft and DMFT. Severe asthmatics presented significantly the lowest sIgA mean level (23.61 ± 5.33) and the most reduced saliva flow rate (0.64 ± 0.20). Conclusion: The reduction in saliva flow rate and secretory immunoglobulin A render asthmatic children more prone to increased dental caries progression mainly of primary dentition.


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