International Journal of Clinical Pediatric Dentistry

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VOLUME 12 , ISSUE 3 ( May-June, 2019 ) > List of Articles

Original Article

Comparative Evaluation of Remineralization Potential of Two Varnishes Containing CPP–ACP and Tricalcium Phosphate: An In Vitro Study

Venu Varma, K Sundeep Hegde, Sharan S Sargod, HT Ajay Rao

Keywords : Clinpro varnish, MI varnish with CPP–ACP, Tooth remineralization

Citation Information : Varma V, Hegde KS, Sargod SS, Rao HA. Comparative Evaluation of Remineralization Potential of Two Varnishes Containing CPP–ACP and Tricalcium Phosphate: An In Vitro Study. Int J Clin Pediatr Dent 2019; 12 (3):233-236.

DOI: 10.5005/jp-journals-10005-1629

License: CC BY-NC 4.0

Published Online: 01-03-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Aim: The aim of this study is to evaluate the remineralization potential of Clinpro XT varnish containing tricalcium phosphate (TCP) and MI varnish containing casein phosphopeptide (casein phosphopeptide–amorphous calcium phosphate, CPP–ACP). Materials and methods: Thirty premolar teeth were taken and divided into three groups. Samples were sliced mesiodistally into buccal and lingual halves using a diamond disk bur. The buccal halves of the teeth were used for the study. Artificial caries like lesions were produced and evaluated with Diagnodent. The samples in each group were treated with the respective remineralizing agent (except for the control group) at every 24 hours for 7 days and the surfaces were assessed using Diagnodent to record the values after the remineralization procedure. The Diagnodent values obtained were tabulated and statistically analyzed using one-way ANOVA and Tukey's multiple comparison tests. Results: There was a significant difference between the values calculated before and after remineralization in all the three groups. Conclusion: The study findings showed that MI varnish containing CPP–ACP had the highest release of fluoride as compared to the Clinpro fluoride releasing varnish. Clinical significance: MI varnish is a 5% NaF varnish containing CPP–ACP to give an exceptional fluoride varnish that releases more bioavailable fluoride, calcium, and phosphate, hence, can be used successfully in remineralization of early carious lesions. CPP–ACP can be used in the clinical practice for reversing or arresting the early carious lesions.

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